Bangla BCRDV ® Vac

Bangla BCRDV ® Vac

Bangla GumboroVac®

Intermediate-Plus strain of IBDV

Live freeze-dried Vaccine against Infectious bursal disease (Gumboro).

Composition:

Bangla GumboroVac is a freeze-dried vaccine containing live Intermediate strain of IBDV.

Active components per dose: Live Intermediate-plus BMB 15/07 strain of IBDV:  103.5 EID50 per dose

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Description

Bangla BCRDV (Baby Chick Ranikhet Disease Virus) is a live vaccine against Newcastle Disease in chickens
Composition
  Bangla® BCRDV Vac is a freeze-dried vaccine containing live attenuated Lentogenic F strain of Newcastle Disease virus.

Active components per dose: Live attenuated NDV Lentogenic F strain ≥ 106 EID50 per dose

The freeze-dried pellet contains stabilizers and antibiotics.

Formulation
  A freeze-dried pellet.
Indication
  Bangla® BCRDV Vac is a live freeze-dried vaccine indicated for the immunization of healthy fowls against Newcastle Disease (ND). This vaccine specifically is suited to protect chicks relatively susceptible to bacterial and viral stresses.
Uses and Vaccination Program
  Uses:

Benefits of using Live Bangla® BCRDV vaccine

·         Bangla® BCRDV vaccine contain F-strain of NDV. F-Strain is a virus of low virulence in contrast to other lentogenic strain of NDV such as B1 and LaSota.

·         (Notes: Mean Death Time, MDT minimum lethal dose for chicken embryo of F-strain is 168 hours, whereas MDT of B1 and LaSota Strain are 128 and 103 respectively)

·         In chicks, F-strain virus multiplies slowly in the invaded organ.

·         This vaccine gives maximum protection against NDV and minimum post vaccination reaction in chicks

Vaccination Program

Primary Vaccination with Bangla® BCRDV Vac is suitable and safe for chicks at day old to 5 days of age. Primary vaccination should be done at 3-5 days of age and secondary vaccination should be done at 18-20 days of age.

Immunity
  The first signs of the antibody response are observed one week after vaccination.

In fowls an adequate immunity against ND will last for approximately 6-8 weeks.  For longer protection revaccination is necessary.

Vaccination Reaction
  Post-vaccination reactions have not been observed after the vaccination of healthy fowls.

Duration and intensity of the vaccination reaction and the establishment of a solid immunity are dependent on the health and condition of the fowls. Hygiene and management are also important factors to be considered in the post vaccination period.

Directions For Use
  A. Intranasal/Eye Drop Application

Dissolve the vaccine in supplied solvent or deionized water (Usually 5 ml for 100 doses, 11 ml for 300 doses, 17 ml for 500 doses and 33 ml for 1000 doses) and administered by supplied standardized dropper. One drop should be applied from a height of a few centimetres onto one nostril or eye.

 

 

B. Administration via the drinking water

Mix the dissolved vaccine with water as shown below:

Age of birds Water per 1,000 doses vaccine
2-4 weeks 10 Liter
4-8 weeks 20Liter
       8 weeks or older 40 Liter

C.    Spray Method

Remove the aluminium seal and rubber stopper from a vial of vaccine. Half-fill the vial with cool, distilled water, then replace stopper and shake until vaccine is in solution. Pour vaccine into a clean container. For day old chicks, add approximately use 250 ml of cool water for 1000 birds and for older birds add 500 ml of cool water for 1000 birds.

 

The vaccine medicated water should be spread evenly over the correct number of fowls, at a distance of 30 to 40 cm.

Withdrawal period
  None
Storage
  ·         Store in the dark between 2 ºC and 8 ºC.  Do not freeze.

·         Protect from exposure to direct sunlight.

Package quantities
  Glass Vials each containing 500 and 1000 doses in packs of 10 vials and packed in cardboard boxes.
Further information
A good immune response is reliant on the reaction of an immunogenic agent and a fully competent immune system. Immunogenicity of the vaccine antigen will be reduced by poor storage or inappropriate administration. Immunocompetence of the animal may be compromised by a variety of factors including poor health, nutritional status, genetic factors, concurrent drug therapy and stress. Under certain conditions, for example extreme disease pressure and variant challenge, fully immune birds may succumb to disease. Therefore, successful vaccination may not be synonymous with full protection in the face of a disease challenge.

 

 

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