Bangla ND Vac®

Bangla ND Vac®

Viscerotropicvelogenicstrain of NDV

Water in oil emulsified Inactivated Vaccine against Newcastle Disease

Composition:

Bangla ND Vac is a inactivated vaccine containing Viscerotropicvelogenicstrain of Newcastle Disease virus. Suspended in the aqueous phase of an oil adjuvant emulsion.Active components per dose: Viscerotropicvelogenicstrain:  108 EID50 per dose (Before Inactivation).

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Description

Bangla ND Vac®

  Bangla® ND Vac is an inactivated vaccine for the immunization of chickens against Newcastle Disease
Composition  
  Inactivated Bangla® ND Vac vaccine containing Viscerotropic Velogenic strain of Newcastle Disease Virus, inactivated with B-lactum and suspended in the aqueous phase of an oil adjuvant emulsion.

Vaccine Characteristics:

·         The oil adjuvant, used in this vaccine acts as stimulus of defense mechanism and disperse antigen slowly.

·         Induce early high antibody level.

·         Less stress. Good absorption with negligible vaccine residue at the site of injection

·         Easy to inject.

Contents  
  Each 0.5 ml dose contains:

NDV inducing minimum HA titre in the allantoic Fluid before inactivation……8log2

Formulation  
  The vaccine appears in the form of a whitish Water-in-oil emulsion.
Indication  
  The vaccine is recommended for the vaccination of broiler, laying and breeding birds to Prevent mortality and clinical signs and to reduce infection caused by Newcastle Disease.
Uses and Vaccination Program  
  Uses:

Benefit of uses of Bangla ND vac in combination with live ND vaccine, like Bangla BCRDV

·         Produce high and long lasting immunity throughout the life.

·         Ensure consistency of protection for flock against vvNDV.

·         This inactivated oil-emulsion vaccine is not as adversely affected by maternal immunity (MDA) as Live vaccines (live vaccine virus may be neutralized by higher level of MDA) because the oil adjuvant vaccine acts as stimulus of defense mechanism and disperse antigen slowly.

·         Reduce respiratory problem.

Vaccination program for Broiler:

·         Vaccinate 0.25 ml per bird at day old in the hatchery.

·         Alternatively, vaccinate commercial broiler with full dose of 0.5 ml per bird at 5-7 days of age after prime up with live vaccine Bangla BCRDV at 3-4days of age.

·         In broiler this vaccination program can reduce the cost of treatment of respiratory problems, since respiratory virus especially NDV are strongly licked to C.R.D and E. Coli infection.

Vaccination program For Layer and breeder:

·         The first vaccination: 0.5 ml per bird at 7 to 14 days of age.

·         Second Dose: 0.5 ml per bird at 17 to 18 weeks of age (2-3 weeks before the start of Production).

·         Depending upon the levels of antibody oh the birds, this vaccine can be applied every 4-6 month to maintain a high and consistent antibody level in birds during production.

 

Dosage and administration  
  Dose: 0.5 ml vaccine per bird by subcutaneous injection in the back of the neck or by intramuscular injection in the thigh or chest muscle, using a medium-sized needle (20g x ½”).

Allow the vaccine to reach ambient temperature (15 – 25°C) before use.

Immunity  
  Active immunity develops within 3-4 weeks and is maintained for 4 month

(For optimal effect of this vaccination, birds must be primed with Live vaccines such as Bangla® BCRDV  against NDV during early age)

Vaccination Reaction  
  In healthy birds no clinical reaction to vaccination will be observed. For some cases, a slight swelling may be felt at the site of vaccination. Local tissue reaction at the site of injection can occur and persist for a variable amount of time.
Withdrawal period  
  None
Disposal advice:  
  Any unused veterinary medicinal product or waste material derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
Package quantities  
  PET bottles containing 250ml (500 Dose) and 500 ml (1000 doses). The bottles are closed with a nitryl rubber stopper and sealed with a coded aluminum cap.
Further information  
  A good immune response is reliant on the reaction of an immunogenic agent and a fully competent immune system. Immunogenicity of the vaccine antigen will be reduced by poor storage or inappropriate administration. Immunocompetence of the birds may be compromised by a variety of factors including poor health, nutritional status, genetic factors, concurrent drug therapy and stress. Under certain conditions, for example extreme disease pressure and variant challenge, fully immune birds may succumb to disease. Therefore, successful vaccination may not be synonymous with full protection in the face of a disease challenge.

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